Investigator's information
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| IDENTIFICATION AND CONTACT INFORMATION |
| Last name: | Borgland |
First name: | Stephanie L |
| Address: | Dept Anesthesiology Pharmacology & Ther.
University of British Columbia
Rm 212, 2nd Floor, Medical Sciences Bloc
2176 Health Sciences Mall
Vancouver (British Columbia)
V6T 1Z3 |
Fax: | (604) 822-6012 |
| BC academic affiliation: | University of British Columbia |
| Department: | Anesthesiology, Pharmacology and Therapeutics |
| E-mail address: |
borgland@interchange.ubc.ca |
BC research location(s): |
University of British Columbia - Vancouver Campus |
| Web Page: |
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MSFHR Research Unit(s): |
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| Status: | Researcher |
| Last update: |
03/11/2009
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| TRAINING AND CREDENTIALS |
| Diploma / Credentials |
Specialty |
Year |
Institution |
| Cellular Biology of Addiction course |
Addiction |
2005 |
Cold Spring Harbour Laboratory |
| Doctorate (PhD) |
Neuropharmacology |
2002 |
University of Sydney |
| Summer Lecture Series on Brain Dysfunction |
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2001 |
RIKEN Brain Science Institute |
| Master's |
Pharmacology |
1997 |
The University of Manitoba |
| Bachelor's |
Biology |
1994 |
University of Victoria |
| Last update: |
04/02/2008
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| AREAS OF EXPERTISE |
| Area of research: |
Health sciences |
| Disciplines trained in: |
Neurosciences
Pharmacology |
| Research disciplines: |
Neurosciences
Pharmacology |
| Research topics: |
Motivations and Emotions (Neurosciences, Mental Health and Addiction)
Drug Abuse (Neurosciences, Mental Health and Addiction)
Neuronal and Synaptic Activity (Neurosciences, Mental Health and Addiction)
Learning and Memory (Neurosciences, Mental Health and Addiction)
Schizophrenia (Neurosciences, Mental Health and Addiction) |
| Fields of application: |
Biomedical Aspects of Human Health
Pathogenesis and Treatment of Diseases |
| Last update: |
03/11/2009
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| TECHNOLOGICAL APPLICATIONS |
| Technological applications: |
Peptides, proteins, enzymes
Psychotropic drugs |
| Last update: |
03/11/2009
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| RESEARCH ACTIVITIES - Description used by investigators to specify their area of expertise. |
| Key words: |
Electrophysiology, Synaptic Plasticity, Immunohistochemistry, Behavior, Pharmacology, Neuroscience, Motivation, Addiction, Dopamine, Neuropeptides |
| Research interests: |
My main interest lies in understanding the neurobiological mechanisms responsible for the homeostatic regulation of brain reward circuits and how drugs of abuse can hijack normal appetitive behaviour. I use slice electrophysiology to elucidate the synaptic and cellular events and retrograde tracing to answer questions related to neural circuitry underlying the physiological effects. |
| Last update: |
03/11/2009
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| RECENT AND REPRESENTATIVE PUBLICATIONS |
| Authors |
| Title (article or book chapter) |
| Year |
Volume |
Number |
Pages |
Journal or book |
Editors |
City and publishing house |
| Borgland, S.L., Chang, S-J, Bowers, Thompson, JL, Vittoz NM, Floresco, S, M.S., Chou, J., Chen, B., Bonci, A. |
| "Orexin A/Hypocretin1 promotes motivation selectively for highly salient positive reinforcers." |
| 2009 |
29 |
3 |
pp. 11215-11225 |
Journal of Neuroscience |
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| Borgland SL, Taha SA, Sarti F, Fields HL, Bonci A |
| "Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine" |
| 2006 |
49 |
4 |
pp. 589-601 |
Neuron |
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Oxford, Elsevier |
| Borgland SL, Malenka RC, Bonci A |
| "Acute and chronic cocaine-induced potentiation of synaptic strength in the ventral tegmental area: electrophysiological and behavioral correlates in individual rats" |
| 2004 |
24 |
34 |
pp. 7482-7490 |
Journal of Neuroscience |
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Washington, Society for Neuroscience |
| Last update: |
23/10/2009
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| LANGUAGE COMPETENCIES |
| Understand: |
English, French |
| Read: |
English, French |
| Write: |
English |
| Speak: |
English, French |
| Last update: |
03/11/2009
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